Malvern Omnisec

Please contact us for pricing & details. Online orders will not be accepted.

The world’s most advanced multi-detector GPC/SEC system

Malvern Panalytical's OMNISEC is a Gel Permeation Chromatography (GPC) / Size Exclusion Chromatography (SEC) system for the measurement of absolute molecular weight, molecular size, intrinsic viscosity, branching and other parameters. It includes OMNISEC RESOLVE, the integrated GPC/SEC module, OMNISEC REVEAL, the integrated multi-detector module and OMNISEC software for the characterization of synthetic and natural polymers, and proteins.


Features and benefits

OMNISEC is a powerful tool for taking control of the performance, quality and value of your product, whether that’s a synthetic polymer in industry, a natural polymer or polysaccharide used in food or pharmaceutical products, or a protein or antibody used in biopharmaceuticals.

As a research tool, it accelerates research into these molecules by providing absolute information for a wide range of applications making it an ideal tool for universities. It reduces service expense and downtime and increases productivity with easy-to-use intuitive software.



  • The ultimate in advanced detection for GPC/SEC and UPLC/UHPLC
  • Fully integrated temperature controlled detector module for improved detector stability and sample characterization
  • More reliable measurements with market leading light scattering sensitivity
  • Measure low concentration samples with a highly sensitive and stable refractive index detector
  • Improved structural comparisons enabled with the unique mechanical auto balance of the differential viscometer
  • See the full range of your samples UV absorbance with the UV-PDA



  • Fully integrated into the OMNISEC software and hardware platform to offer a complete GPC/SEC solution from a single vendor. 
  • Combined pump, degasser, autosampler and column oven in a single module.
  • Improved baseline stability with a Low pulsation pump.
  • Rapid solvent change overs with a low volume degasser giving maximum system productivity. 
  • Temperature controlled Autosampler (4°C – 60°C) to protect thermolabile samples.


OMNISEC Software

  • A single user interface for all system set up, acquisition, and data processing.
  • 1-click from raw data to results! 
  • Multi-Detection analysis to give Absolute Molecular weight, Intrinsic viscosity, concentration data and much more. 
  • Conventional and Universal calibration methods to enable traditional retention volume dependent techniques. 
  • Measure conjugate and copolymer compositions using Compositional analysis – enables direct analysis of application specific Drug Antibody Ratio (DAR), viral Titer and cp/vg ratio.
  • Fully automated system start-up, data acquisition and shut down. All you need to do is insert your vials and press Start! 
  • 21 CFR part 11 compliant for peace of mind operation in a regulated environment.
  • Free software updates for the life of the instrument, no need to worry about expensive upgrade fees! 


SEC-MALS 20 or 9

  • Multi angle light scattering detector to measure absolute molecular weight and molecular size. 
  • Increased confidence of measured data due to the vertical flow cell with radial optics – reduces noise at low angles, increasing data quality!
  • Vertical flow cell eliminates the need to regularly clean the system. 
  • Use as the sole light scattering source on OMNISEC, or add as a powerful additional detector that compliments the RALS/LALS. 



( Download data sheet)